Research and Developments

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September 14, 2013

High Dose Stem Cell Transplant Performed

Posted in: Latest News, Research and Developments

Stem Cells (STEM) has announced the first patient to receive a high dose of one million purified human neural stem cells (HuCNS-SC®) in their Phase 1/2 clinical trial. This followed an independent review by the Data Safety Monitoring Committee, which found no safety issues with proceeding to the high dose. The 16-patient trial is designed to evaluate the
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September 12, 2013

New Stem Cell Eye Treatment Study Beginning

Posted in: Latest News, Research and Developments

(Updated March 12, 2017) MD Stem Cells has announced a new and extensive stem cell study  to determine effectiveness of stem cells in ophthalmic disease. The company has been named collaborator for the new Stem Cell Ophthalmology Treatment Study (SCOTS), being conducted in Florida. Conditions eligible for the new study include retinal diseases such as age-related
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September 2, 2013

Statin Therapy Lowers Risk of Cataracts

Posted in: Latest News, Research and Developments

by Dan Roberts Statin therapy has been shown to reduce inflammation in the retina, but there has been some concern about cataract development for those who use the drugs. In a press conference at the European Society of Cardiology meeting, Aug 30, 2013, John B. Kostis, MD (UMDNJ-Robert Wood Johnson Medical School, New Brunswick, N.J.)
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August 29, 2013

“As-Needed” Injections Are an Option for Wet AMD

Posted in: Latest News, Research and Developments, Therapies, Treatments, and Procedures

Two-year results from the recently-completed HARBOR trial showed that some patients with wet AMD fare as well from Lucentis (ranibizumab) injections on an as-needed basis compared to a monthly basis. The original Lucentis trial recommended monthly dosing until the eye stabilized. The follow-up study, however, found that 93% of patients responded well with an average
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August 27, 2013

Lampalizumab Effective in Slowing Progression of Dry AMD

Posted in: Latest News, Research and Developments

Roche Pharmaceutical has announced positive phase II results from their MAHALO phase II study of lampalizumab (aka anti-factor D). The study showed a 20.4 percent reduction in progression of advanced dry macular degeneration (geographic atrophy) at 18 months. Lampalizumab is designed to inhibit Complement Factor D, a protein that is part of the alternative complement
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August 22, 2013

Support Groups Can Improve Quality of Life

Posted in: Daily Living, Latest News, Research and Developments

by Dan Roberts Researchers have found that facilitated patient support groups can significantly improve visual quality of life (VQoL) for visually impaired people. Twenty-nine groups of up to six patients each were recruited for participation in a “peer group emotional support service” facilitated by trained counselors for a period of six months. Their responses to
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August 21, 2013

Improving Autophagy Function Reduces Drusen

Posted in: Latest News, Research and Developments

by Dan Roberts Researchers at the University of Eastern Finland have discovered that a cleaning mechanism in the center of the retina may be faulty in people who develop age-related macular degeneration (AMD). A cleaning process called autophagy helps clear cellular waste deposits (drusen) that can build up in the retinal tissue. If autophagy diminishes,
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August 15, 2013

Study of aquaporins could hold clues to cataract

Posted in: Latest News, Research and Developments

Researchers have achieved dynamic, atomic-scale views of a protein needed to maintain the transparency of the lens in the human eye. The work, funded in part by the National Institutes of Health, could lead to new insights and drugs for treating cataract and a variety of other health conditions. Aquaporin proteins form water channels between
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July 23, 2013

Disparities in Eye Care Could Cost Some Their Sight

Posted in: Latest News, Research and Developments

Low-income, less educated don’t have same access to preventive treatments, researchers report By Robert Preidt THURSDAY, July 18 (HealthDay News) — Americans with low incomes and education levels are less likely to get eye care, a new study finds. Researchers examined data from nearly 3,600 people, aged 40 and older, who took part in the
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July 20, 2013

Gene Therapy Without Retinal Risk

Posted in: Latest News, Research and Developments, Therapies, Treatments, and Procedures

Researchers have developed a method of delivering genes to the inner layers of the retina without the risks associated with injection into the delicate tissues themselves. This less invasive technique has been carried out successfully in animal models by a research team led by Drs. John G. Flannery and David V. Schaffer at the University
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