Research and Developments

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September 27, 2013

Saving the sight of premature babies

Posted in: Latest News, Research and Developments

Researchers at Australia’s Vision Centre have announced in a press release that treatment with near-infrared (NIR) light can prevent the development of retinopathy of prematurity (ROP). Using animal models that mimic the disease, Vision Centre researchers report that shining gentle near-infrared light (NIR) at 670 nanometres (nm) is a potential treatment that is less invasive,
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September 20, 2013

Statin Use Associated With Cataracts

Posted in: Latest News, Research and Developments

Statin drugs are known to reduce cholesterol, which benefits the retina. The medications may, however, also increase the risk of cataracts, according to a report published September 19, 2013 in the Journal of the American Medical Association. An analysis of 6,972 subjects showed that those taking the medication had a 9% higher risk of cataract
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September 17, 2013

C3 Gene Variant Linked To Macular Degeneration

Posted in: Latest News, Research and Developments

Researchers report that a change in the C3 gene, which plays a role in inflammation and in the body’s immune response, also contributes to macular degeneration. After sequencing DNA from 10 regions of the genome that had been previously linked to AMD in previous genetic studies, the researchers turned up two gene variants: one in the
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September 14, 2013

High Dose Stem Cell Transplant Performed

Posted in: Latest News, Research and Developments

Stem Cells (STEM) has announced the first patient to receive a high dose of one million purified human neural stem cells (HuCNS-SC®) in their Phase 1/2 clinical trial. This followed an independent review by the Data Safety Monitoring Committee, which found no safety issues with proceeding to the high dose. The 16-patient trial is designed to evaluate the
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September 12, 2013

New Stem Cell Eye Treatment Study Beginning

Posted in: Latest News, Research and Developments

(Updated March 12, 2017) MD Stem Cells has announced a new and extensive stem cell study  to determine effectiveness of stem cells in ophthalmic disease. The company has been named collaborator for the new Stem Cell Ophthalmology Treatment Study (SCOTS), being conducted in Florida. Conditions eligible for the new study include retinal diseases such as age-related
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September 2, 2013

Statin Therapy Lowers Risk of Cataracts

Posted in: Latest News, Research and Developments

by Dan Roberts Statin therapy has been shown to reduce inflammation in the retina, but there has been some concern about cataract development for those who use the drugs. In a press conference at the European Society of Cardiology meeting, Aug 30, 2013, John B. Kostis, MD (UMDNJ-Robert Wood Johnson Medical School, New Brunswick, N.J.)
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August 29, 2013

“As-Needed” Injections Are an Option for Wet AMD

Posted in: Latest News, Research and Developments, Therapies, Treatments, and Procedures

Two-year results from the recently-completed HARBOR trial showed that some patients with wet AMD fare as well from Lucentis (ranibizumab) injections on an as-needed basis compared to a monthly basis. The original Lucentis trial recommended monthly dosing until the eye stabilized. The follow-up study, however, found that 93% of patients responded well with an average
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August 27, 2013

Lampalizumab Effective in Slowing Progression of Dry AMD

Posted in: Latest News, Research and Developments

Roche Pharmaceutical has announced positive phase II results from their MAHALO phase II study of lampalizumab (aka anti-factor D). The study showed a 20.4 percent reduction in progression of advanced dry macular degeneration (geographic atrophy) at 18 months. Lampalizumab is designed to inhibit Complement Factor D, a protein that is part of the alternative complement
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August 22, 2013

Support Groups Can Improve Quality of Life

Posted in: Daily Living, Latest News, Research and Developments

by Dan Roberts Researchers have found that facilitated patient support groups can significantly improve visual quality of life (VQoL) for visually impaired people. Twenty-nine groups of up to six patients each were recruited for participation in a “peer group emotional support service” facilitated by trained counselors for a period of six months. Their responses to
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August 21, 2013

Improving Autophagy Function Reduces Drusen

Posted in: Latest News, Research and Developments

by Dan Roberts Researchers at the University of Eastern Finland have discovered that a cleaning mechanism in the center of the retina may be faulty in people who develop age-related macular degeneration (AMD). A cleaning process called autophagy helps clear cellular waste deposits (drusen) that can build up in the retinal tissue. If autophagy diminishes,
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