Research and Developments

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June 24, 2014

Squalamine Eye Drops Under Study for Wet AMD

Posted in: Latest News, Research and Developments

(Updated 4/17/16) On June 24, 2014, Ohr Pharmaceutical, Inc. announced positive top-line interim results for its Phase 2 clinical trial of Squalamine eye drops in patients with wet age-related macular degeneration (wet AMD). The data demonstrated a positive benefit in multiple visual function including a gain in visual acuity of +10.4 letters with Squalamine eye
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June 17, 2014

Omega-3 Inhibits Retinal Blood Vessel Growth

Posted in: Latest News, Research and Developments

Researchers from Massachusetts Eye and Ear/Schepens Eye Research Institute, Harvard Medical School and other institutions have demonstrated for the first time that the omega-3 long-chain polyunsaturated fatty acids (LCPUFAs), DHA and EPA, can inhibit choroidal neovascularization (CNV). Their findings will be published in PNAS Online Early Edition the week of June 16-20, 2014. “These are
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June 12, 2014

Stem Cell Trial for Myopic Macular Degeneration

Posted in: Latest News, Research and Developments

Advanced Cell Technology (ACT) announced in a shareholders’ conference call on June 9, 2014, that it has initiated its myopic macular degeneration (MMD) trial at Jules Stein Eye Institute at UCLA. The open-label study will enroll 12 patients, with cohorts of 3 patients each in an ascending dosage format. As with it’s current trials for
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June 5, 2014

Making artificial vision look more natural

Posted in: Latest News, Research and Developments

Courtesy: National Eye Institute, National Institutes of Health (NEI/NIH) NIH-funded study could help improve retinal prosthetic devices In laboratory tests, researchers have used electrical stimulation of retinal cells to produce the same patterns of activity that occur when the retina sees a moving object. Although more work remains, this is a step toward restoring natural,
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May 12, 2014

Summary of Research and Developments, 2013-2014

Posted in: Research and Developments

by Dan Roberts View an audio/visual version of this presentation. This has been a year of watching and waiting, as many studies and clinical trials are bearing down on promising treatments and cures for retinal diseases. My ninth annual report will offer brief descriptions of the work done in pharmaceutical treatments, anti-VEGF and combination therapies
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April 29, 2014

Experimental Therapies for CSR

Posted in: Research and Developments, Therapies, Treatments, and Procedures

by Dan Roberts April 2014 Updated September 8, 2015 Research has shown that corticosteroids produced by the body (endogenous) and administered externally (exogenous) can raise adrenaline levels, which can harm the central retina. Some people have high levels of endogenous steroids that can lead to a condition called central serous retinopathy (CSR), aka central serous
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April 16, 2014

Smart Contact Lenses For the Blind

Posted in: Latest News, Research and Developments

Google has taken their new Google Glass technology a step further with an idea that could have significant benefits for the blind. The company has applied for a patent for a contact lens containing a built-in camera. With this, a blind person would be able, for example, to receive an audible signal warning of an
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March 29, 2014

Blindness and Visual Impairment Rates Have Fallen

Posted in: Latest News, Research and Developments

234 out of 15,000 studies between 1980 and 2012 have shown that rates of blindness and visual impairment have decreased significantly in developed countries during the past two decades. Macular degeneration now appears to be the leading cause of chronic vision loss, surpassing cataracts and glaucoma. The most common cause of partial vision impairment continues
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January 29, 2014

Seniors With Wet AMD Now Less Likely to Need Long-Term Care

Posted in: Latest News, Research and Developments

Researchers have looked at a sample population of senior adults newly diagnosed with wet age-related macular degeneration (exudative, or neovascular, AMD) and found that those who received either Lucentis or Avastin injections* were 19% less likely to be admitted to a long-term care facility during the follow-up period. The reason? The introduction of anti-VEGF therapy
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January 18, 2014

Findings Help Predict AMD Advancement

Posted in: Latest News, Research and Developments

A 10-year follow-up study of participants in the original AREDS trial has been completed. The Age-Related Eye Disease Study Research Group revealed new statistics on the risk and rate of progression from early to advanced age-related macular degeneration (AMD). Participants aged 55 to 80 years with no AMD or AMD of varying severity were followed
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