Research and Developments

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November 13, 2013

ALG-1001 to Treat Vitreomacular Traction and DME

Posted in: Research and Developments

(Updated 8/10/17) In November 2013, Allegro Ophthalmics, LLC announced the commencement of a Phase II study of ALG-1001 in patients with vitreomacular traction (VMT). The study evaluated the safety and efficacy of intravitreal injections of ALG-1001 in patients with VMT. Patients were enrolled at multiple sites outside the United States, with the primary efficacy endpoint of non-surgical release of
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November 8, 2013

Breakthrough Technology Helps People See With Their Ears

Posted in: Latest News, Research and Developments

OrCam, an Israel-based company, has developed a camera-based system which allows the visually impaired to both read and identify objects with a point of a finger. The OrCam device is a small camera connected by a thin cable to a portable computer in the wearer’s pocket. The system clips on to the wearer’s glasses with
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October 31, 2013

Gene Therapy Effective in Dogs With Cone-Rod Dystrophy

Posted in: Latest News, Research and Developments

As reported October 29, 2013 in the journal Molecular Therapy, a French research team led by Fabienne Rolling, Ph.D., of INSERM has used gene therapy to restore vision in dogs affected by cone-rod dystrophy. CRD is caused by mutations in the gene RPGRIP1. In this study, retinal cone cell (central vision) function was significantly rescued
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October 18, 2013

Predictors of Advanced AMD Defined

Posted in: Latest News, Research and Developments

According to members of the Three Continent AMD Consortium (3CC), prediction models for age-related macular degeneration (AMD) based on case-control studies have a tendency to overestimate risks. To provide more well-defined data, 3CC developed a prediction model for late AMD based on data from population-based studies. Using data from the Rotterdam Study, the Beaver Dam
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September 27, 2013

Saving the sight of premature babies

Posted in: Latest News, Research and Developments

Researchers at Australia’s Vision Centre have announced in a press release that treatment with near-infrared (NIR) light can prevent the development of retinopathy of prematurity (ROP). Using animal models that mimic the disease, Vision Centre researchers report that shining gentle near-infrared light (NIR) at 670 nanometres (nm) is a potential treatment that is less invasive,
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September 20, 2013

Statin Use Associated With Cataracts

Posted in: Latest News, Research and Developments

Statin drugs are known to reduce cholesterol, which benefits the retina. The medications may, however, also increase the risk of cataracts, according to a report published September 19, 2013 in the Journal of the American Medical Association. An analysis of 6,972 subjects showed that those taking the medication had a 9% higher risk of cataract
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September 17, 2013

C3 Gene Variant Linked To Macular Degeneration

Posted in: Latest News, Research and Developments

Researchers report that a change in the C3 gene, which plays a role in inflammation and in the body’s immune response, also contributes to macular degeneration. After sequencing DNA from 10 regions of the genome that had been previously linked to AMD in previous genetic studies, the researchers turned up two gene variants: one in the
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September 14, 2013

High Dose Stem Cell Transplant Performed

Posted in: Latest News, Research and Developments

Stem Cells (STEM) has announced the first patient to receive a high dose of one million purified human neural stem cells (HuCNS-SC®) in their Phase 1/2 clinical trial. This followed an independent review by the Data Safety Monitoring Committee, which found no safety issues with proceeding to the high dose. The 16-patient trial is designed to evaluate the
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September 12, 2013

New Stem Cell Eye Treatment Study Beginning

Posted in: Latest News, Research and Developments

(Updated March 12, 2017) MD Stem Cells has announced a new and extensive stem cell study  to determine effectiveness of stem cells in ophthalmic disease. The company has been named collaborator for the new Stem Cell Ophthalmology Treatment Study (SCOTS), being conducted in Florida. Conditions eligible for the new study include retinal diseases such as age-related
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September 2, 2013

Statin Therapy Lowers Risk of Cataracts

Posted in: Latest News, Research and Developments

by Dan Roberts Statin therapy has been shown to reduce inflammation in the retina, but there has been some concern about cataract development for those who use the drugs. In a press conference at the European Society of Cardiology meeting, Aug 30, 2013, John B. Kostis, MD (UMDNJ-Robert Wood Johnson Medical School, New Brunswick, N.J.)
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