Research and Developments

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July 23, 2013

Disparities in Eye Care Could Cost Some Their Sight

Posted in: Latest News, Research and Developments

Low-income, less educated don’t have same access to preventive treatments, researchers report By Robert Preidt THURSDAY, July 18 (HealthDay News) — Americans with low incomes and education levels are less likely to get eye care, a new study finds. Researchers examined data from nearly 3,600 people, aged 40 and older, who took part in the
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July 20, 2013

Gene Therapy Without Retinal Risk

Posted in: Latest News, Research and Developments, Therapies, Treatments, and Procedures

Researchers have developed a method of delivering genes to the inner layers of the retina without the risks associated with injection into the delicate tissues themselves. This less invasive technique has been carried out successfully in animal models by a research team led by Drs. John G. Flannery and David V. Schaffer at the University
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July 19, 2013

Gene Expression in the Retina Expanded

Posted in: Latest News, Research and Developments

Identifying the genetics of retinal degeneration has become especially important with progress of trials in gene therapy. Investigators have identified more than 200 retinal degeneration disease genes, but still haven’t been able to find the cause of disease in up to half of cases. Now Ocular Genomics Institute has announced that Drs. Michael Farkas, Eric
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July 6, 2013

What Should I Ask My Doctor?

Posted in: Daily Living, Eye Conditions, Health and Nutrition, Research and Developments, Therapies, Treatments, and Procedures

by Dan Roberts Updated July 2013 One of the most common problems encountered by people who are first diagnosed with macular degeneration is what to ask the doctor. The news usually takes us by surprise, and we may have never even heard of the disease before. To compound our confusion, many doctors do not have
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July 6, 2013

What is a Clinical Trial?

Posted in: Research and Developments

(From “The First Year: Age-Related Macular Degeneration,” (Sep 2006) by Daniel L. Roberts) A clinical trial involves direct observation of a living patient to answer specific questions about vaccines, therapies, or new methods. It is designed in four phases, during which rigorous protocols must be followed under FDA guidelines: Phase I: Determination of safety and
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June 21, 2013

New Anti-PDGF Aptamer Now in Trials

Posted in: Research and Developments

by Dan Roberts February 15, 2008 Ophthotech has begun the first phase of a clinical trial of E10030, an anti-platelet derived growth factor aptamer being developed for treating wet AMD. The trial will evaluate the safety and tolerability of E10030 in combination with an antiangiogenic drug. The hope is that the combination will result in
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June 1, 2013

Summary of Research and Developments in Macular Degeneration, 2012-2013

Posted in: Research and Developments

by Dan Roberts June 2013 INTRODUCTION This is a summary of reports about significant research and development in the field of macular degeneration and related diseases presented since June 2012 and May 2013. I will briefly describe the conclusions of 77 studies that have been presented in the areas of therapy, prevention, technology, nutrition and
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May 30, 2013

A Guide to Research in Dry AMD

Posted in: Research and Developments

Compiled by Dan Roberts (Updated March 2017) This is a guide to all leading research to date in the field of dry age-related macular degeneration (AMD). It is divided into three categories: Pharmaceutical Gene Therapy Surgical Intervention Most headings contain links to further information. Hopefully, this document will help to identify information of interest specifically to
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April 6, 2013

How Many People are Legally Blind from Wet AMD?

Posted in: Eye Conditions, Research and Developments

by Dan Roberts April 2013 The latest report I have seen that provides anything close to an accurate estimate of legal blindness among people with wet age-related macular degeneration (AMD) is Wilmer Eye Institute’s “Causes and prevalence of visual impairment among adults in the United States” by Congdon N, et al (Arch Ophthalmol. 2004 Apr;122(4):477-85).
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March 21, 2013

Stem Cells Found in Human Breast Tissue

Posted in: Latest News, Research and Developments

by Dan Roberts In March of 2013, an online early edition of the Proceedings of the National Academy of Sciences reported that newly discovered stem cells from human breast tissue are more genetically stable than the human induced pluripoint stem cells (hiPS cells) currently being developed. In addition to avoiding the issue of using embryonic
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