Research and Developments

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April 22, 2011

Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration

Posted in: Research and Developments

The CATT Research Group April 2011 In 2005, clinical trials established the efficacy of ranibizumab (Lucentis, Genentech) for the treatment of neovascular age-related macular degeneration (AMD), the leading cause of legal blindness in the United States. While awaiting approval for ranibizumab from the Food and Drug Administration, ophthalmologists began treating neovascular AMD with off-label use
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September 14, 2010

A Primer on the Use of Stem Cells in Ophthalmology

Posted in: Research and Developments

Irving J. Arons September 2, 2010 (Version 3, Updated September 14, 2010) I recently came across an interesting news release from International Stem Cell Corporation (ISCO) announcing that it had formed a new business unit, Cytovis, to focus on stem cell programs in ophthalmology, including CytoCor for the cornea and CytoRet for the retina. That
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July 22, 2010

Spikes in IOP May Result From Particulate Matter in Avastin

Posted in: Research and Developments

by Dan Roberts In a presentation to Hawaiian Eye 2010, Malik Y. Kahook, MD, said that Avastin (bevacizumab) stored for long periods of time shows evidence of increased large particulate matter. This debris can block the eye’s trabecular network and lead to increased intraocular pressure (IOP) in patients being treated with the drug for wet
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June 1, 2010

Summary of Research and Developments in Macular Degeneration: 2009-2010

Posted in: Research and Developments

by Dan Roberts June 10, 2010 Introduction If I were to describe the past twelve months in a word, it would be “progress.” No spectacular breakthroughs have occurred during that time to make big news in the AMD world, but a lot of persistent work has been reaping promising results. moving us ever closer to
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May 16, 2010

Genetic testing sheds light on degenerative eye disease

Posted in: Latest News, Research and Developments

Press Release February 13, 2007 Updated 5/16/2010 ANN ARBOR, Mich. — Genetic testing for eye disease is providing vital information about complex retinal diseases, especially when used to confirm a clinician’s diagnosis. In a newly published review of such tests that were conducted over a five-year period at the University of Michigan Kellogg Eye Center,
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February 3, 2010

Study Shows Lucentis and Avastin to be Equal

Posted in: Latest News, Research and Developments

by Dan Roberts February 3, 2010 Investigators at Kaiser Permanente Southern California in Pasadena reported in the February 2010 issue of Ophthalmology that Avastin and Lucentis performed equally in recent testing. In an indirect comparison of the two drugs, study author Dr. Donald Fong and coauthors reviewed the records of 452 patients treated for wet
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January 30, 2010

PEG-POD – New Gene Delivery Tool

Posted in: Latest News, Research and Developments

by Dan Roberts January 2010 Researchers have developed a new tool for gene therapy that significantly increases gene delivery to cells in the retina compared to other carriers and DNA alone. The study was published in the January 2010 issue of The Journal of Gene Medicine by Tufts University School of Medicine and the Sackler
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November 30, 2009

Blue Light Filtering IOLs May Slow AMD

Posted in: Research and Developments

by Dan Roberts November 2009 A 2009 study* has shown that implantation of a blue light-filtering intraocular lens (IOL) at the time of cataract surgery increases macular pigment in the retina. This increase may provide protection against the development and/or progression of AMD. The study was reported by the Macular Pigment Research Group at the
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October 27, 2009

Brachytherapy May Reduce Burden of Treatment and Further Improve Visual Acuity

Posted in: Research and Developments, Therapies, Treatments, and Procedures

San Francisco, CA (PRWEB) October 27, 2009 — NeoVista, Inc. made public at the American Academy of Ophthalmology meeting the company’s interim study results from the preliminary study MERITAGE-I. The study was designed to examine the company’s novel epimacular brachytherapy procedure when used in patients that require chronic anti-VEGF treatment for wet AMD. Brachytherapy involves
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June 17, 2009

Lipschitz Macular Implant Allows Bilateral Magnification of Vision

Posted in: Research and Developments

On June 17, 2009, OptoLight Vision Technology announced that it received a CE mark for its Lipshitz Macular Implant (LMI), named for its inventor, Isaac Lipshitz. This will allow OptoLight to immediately begin marketing the implant in Europe and other markets outside of the United States. On December 28, 2007, Optolight Vision Technology announced success
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