Research and Developments

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November 30, 2009

Blue Light Filtering IOLs May Slow AMD

Posted in: Research and Developments

by Dan Roberts November 2009 A 2009 study* has shown that implantation of a blue light-filtering intraocular lens (IOL) at the time of cataract surgery increases macular pigment in the retina. This increase may provide protection against the development and/or progression of AMD. The study was reported by the Macular Pigment Research Group at the
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October 27, 2009

Brachytherapy May Reduce Burden of Treatment and Further Improve Visual Acuity

Posted in: Research and Developments, Therapies, Treatments, and Procedures

San Francisco, CA (PRWEB) October 27, 2009 — NeoVista, Inc. made public at the American Academy of Ophthalmology meeting the company’s interim study results from the preliminary study MERITAGE-I. The study was designed to examine the company’s novel epimacular brachytherapy procedure when used in patients that require chronic anti-VEGF treatment for wet AMD. Brachytherapy involves
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June 17, 2009

Lipschitz Macular Implant Allows Bilateral Magnification of Vision

Posted in: Research and Developments

On June 17, 2009, OptoLight Vision Technology announced that it received a CE mark for its Lipshitz Macular Implant (LMI), named for its inventor, Isaac Lipshitz. This will allow OptoLight to immediately begin marketing the implant in Europe and other markets outside of the United States. On December 28, 2007, Optolight Vision Technology announced success
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June 11, 2009

Summary of Research and Developments in Macular Degeneration: 2008-2009

Posted in: Research and Developments

by Dan Roberts June 11, 2009 Laser Rejuvenates the Retina According to a study announced at the Euretina Congress in May 2008, a laser treatment that “cleans up” Bruch’s membrane may slow down the progression to AMD. Bruch’s membrane is the tissue that separates the photoreceptor cells (our sight cells) from the nourishing blood vessel
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April 22, 2009

siRNA Turns Off Bad Genes

Posted in: Research and Developments

by Dan Roberts (updated April 2009) A new type of anti-VEGF drug called “small interference RNA (siRNA),” is showing promise in its ability to turn off genes that cause wet AMD. A preliminary primate study in early 2004 showed that, at the highest dose used in the study siRNA (formerly called RNAi) “reduced the incidence
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November 20, 2008

Brain Reorganizes to Adjust for Loss of Vision

Posted in: Research and Developments

Atlanta (November 20, 2008) – A new study from Georgia Tech shows that when patients with macular degeneration focus on using another part of their retina to compensate for their loss of central vision, their brain seems to compensate by reorganizing its neural connections. Age related macular degeneration is the leading cause of vision loss
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November 10, 2008

Interleukin-6 and Interleukin-8 Linked to Dry AMD

Posted in: Research and Developments

by Dan Roberts (Updated November 10, 2008) Concentration of two cytokines, interleukin-6 and interleukin-8, have been found in two different studies to be potential biomarkers for incidence of dry AMD. Cytokines are signaling compounds in the cells that are involved in a variety of immunological, inflammatory, and infectious diseases. Janice C. Law, MD, and her
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September 29, 2008

POT-4 for Treatment of AMD

Posted in: Research and Developments

by Dan Roberts (Updated September 29, 2008) Potentia Pharmaceuticals, Inc. announced on March 20, 2007 that it was entering the clinical phase of development of POT-4 for treatment of age-related macular degeneration (AMD). According to the researchers, POT-4, a synthetic peptide, shuts down the complement activation system that can lead to local inflammation, tissue damage
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September 22, 2008

Pearls from Recent Studies on Low Vision Rehabilitation and Psychosocial Issues

Posted in: Daily Living, Research and Developments

Research of interest to the AMD Community as presented at Vision 2008, Montreal, Canada Selected and Summarized by Dan Roberts, Director, MD Support These findings are derived by the referenced authors based solely upon the results of their respective studies. In every case, more research is recommended before final conclusions can be drawn. Pearl #1.
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August 28, 2008

New Dry AMD Gene Found

Posted in: Latest News, Research and Developments

by Dan Roberts As reported in the Aug. 28, 2008 online edition of the New England Journal of Medicine, researchers have found a genetic link associated with dry AMD. That’s the good news. The bad news is that siRNA drug therapy may increase the risk for dry AMD in patients who have that genetic variant.
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