Research and Developments

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June 1, 2008

Summary of Research and Developments in Macular Degeneration: 2007-2008

Posted in: Research and Developments

Compiled and edited by Dan Roberts JUNE 2007 Omega-3 Proving to be Beneficial on Several Fronts Recent studies have shown that Omega-3 fatty acids and fish consumption may reduce the risks of age-related macular degeneration (AMD), Alzheimer’s disease, inflammation and depression. The Age-Related Eye Disease Study (AREDS) Research Group showed that dietary total Omega-3 and
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April 28, 2008

Gene Therapy Breakthrough

Posted in: Latest News, Research and Developments

by Dan Roberts April 28, 2008 According to two studies published in the New England Journal of Medicine*, doctors have, for the first time, used gene replacement therapy to restore vision in patients with Leber’s congenital amaurosis. Leber’s syndrome is a form of retinitis pigmentosa (RP) that affects children and often leads to blindness by
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March 19, 2008

Müller Cells May Restore Sight

Posted in: Latest News, Research and Developments

by Dan Roberts March 19, 2008 Over the past several years, scientists have been taking an interest in certain cells within the patient’s own eyes as having the potential to transform into stem-like (progenitor) cells. Called Müller glial cells, they would then migrate to damaged areas of the retina and replace dead cells, restoring vision
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March 17, 2008

Robo-4 and Slit2 May Team Up Against Wet AMD

Posted in: Latest News, Research and Developments

by Dan Roberts March 17, 2008 “Robo-4” sounds like a movie by Arnold Schwarzenegger, but in this case, it is a link to another potential treatment for wet AMD. Short for “Roundabout,” Robo-4 is a protein receptor found on the surface of blood vessel cells. When it binds with another protein called Slit2, the combination
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February 28, 2008

CD36 Deficiency May Cause Dry AMD

Posted in: Research and Developments

by Dan Roberts February 2008 CD36 is a protein molecule (called an “integral membrane protein”) permanently attached to the surface of certain human cells. It plays a role in the inflammation process, but researchers have now discovered that a deficiency of the protein may cause the dry form of macular degeneration. Researchers reported that deficiency
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February 28, 2008

AMD Associated With Heart Attack and Stroke

Posted in: Research and Developments

by Dan Roberts Researchers at the University of Sydney have found that people suffering from AMD have twice the risk of dying from heart attack or stroke. 3,654 people aged 49 years old and older, were studied. Five years later, 2,335 people were re-examined, and after 10 years, 1,952 were re-examined. When the study began,
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February 23, 2008

SAILOR Study Results Favorable

Posted in: Latest News, Research and Developments

by Dan Roberts February 23, 2008 The final results from Cohort 1 of the Phase IIIb SAILOR study of Lucentis in patients with wet AMD were presented on February 23, 2008 at the Bascom Palmer Eye Institute’s Angiogenesis meeting by Dr. David Boyer (Retina-Vitreous Associates Medical Group, Los Angeles). The final, one-year data support the
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February 1, 2008

Retina Developed From Human Stem Cells

Posted in: Latest News, Research and Developments

by Dan Roberts (Updated February 1, 2008) Advanced Cell Technology (ACT) in Massachusetts announced on September 23, 2004 that they had engineered human embryonic stem cells which could be used to repair a damaged retina. The research team worked with stem cells taken from human embryos made by another team at Harvard University and coaxed
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December 23, 2007

The First Seven Years: An Overview of Stem Cell Transplantation Research for Treatment of Retinal Disease

Posted in: Research and Developments

by Dan Roberts A great deal has happened in an amazingly short time in the field of stem cell transplantation for treatment of retinal disease. This article overviews the first seven years and briefly summarizes the most important research. By no means comprehensive, it is intended to provide a helpful perspective for both doctors and
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November 23, 2007

Degenerative Myopia

Posted in: Eye Conditions, Research and Developments

by Dan Roberts (Updated November 2015) Overview Myopia is a condition whereby images come into focus in front of the eye, resulting in a blurred image on the retina. The more severe the nearsightedness, the farther the image is from the retina, which results in more blurry vision in the distance. Myopia causes light rays
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