Research and Developments

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August 10, 2016

Is Blindness The “Worst Ailment”?

Posted in: Daily Living, Latest News, Low Vision Rehabilitation, Research and Developments

by Dan Roberts A recent online nationwide poll (1) has joined similar past studies in revealing that people consider vision loss to be the “worst ailment that could happen to them relative to losing memory, speech, hearing, or a limb.” The researchers’ intent was to “underscore the importance of focusing on preservation of eye health and the
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July 27, 2016

Finally, A Promising Breakthrough For Dry AMD

Posted in: Latest News, Research and Developments

Genentech, Inc., a leading pharmaceutical developer, is currently conducting two phase III trials studying the drug lampalizumab as a potential treatment for advanced dry macular degeneration, also known as geographic atrophy (GA). Patients who have been diagnosed with GA are encouraged to participate in the trials, which are being conducted at hundreds of locations in
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July 19, 2016

Anti-depressant Drugs May Someday Help Prevent Macular Degeneration

Posted in: Latest News, Research and Developments

Tests in a mouse model of macular degeneration have shown that anti-depressant drugs already on the market prevent damage to the light cells in the retina. In a study published in Proceedings of the National Academy of Sciences, a University of Wisconsin—Madison research team pinpoints how immune abnormalities beneath the retina result in macular degeneration.
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June 9, 2016

For Some, Switching ANTI-VEGF Treatments Midstream Could Be Harmful

Posted in: Latest News, Research and Developments, Therapies, Treatments, and Procedures

Switching from Lucentis to Eylea could result in worsening of the retinal condition of some people with wet (exudative) AMD. Since the advent of anti-VEGF drug treatments for wet AMD, research has verified that blood vessel growth and leakage (neovascularization) usually diminishes in patients who are switched from either Lucentis or Avastin to Eylea. A small
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May 28, 2016

Summary of Research and Development — 2016

Posted in: Research and Developments

ILVSG Presentation June 2016 Dan Roberts I. INTRODUCTION This is my 11th annual summary of leading research and developments that have occurred during the past 12 months in the field of blindness and low vision. I’ll take the liberty in several cases of quoting the sources, but for the sake of conversational flow, I’ll break
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May 20, 2016

Visual Impairment and Blindness in U.S. May Double by 2050

Posted in: Latest News, Research and Developments

The findings of a recent study suggest that there is a need for increased screening and interventions to identify and address treatable causes of vision loss. With the youngest of the baby boomers hitting 65 by 2029, the number of people with visual impairment or blindness in the United States is expected to double to
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May 5, 2016

OPT-302 Enters Phase 2A Trials for Wet AMD

Posted in: Latest News, Research and Developments

Opthea Limited, a developer of novel biologic therapies for the treatment of eye diseases, has randomized and dosed the first patient in the Phase 2A dose expansion clinical trial of OPT-302 for wet AMD. OPT-302 is a soluble form of vascular endothelial growth factor receptor 3 (VEGFR-3) or ‘Trap’ molecule, that blocks the activity of two
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April 14, 2016

Smoking and AMD—Are E-Cigarettes the Answer?

Posted in: Health and Nutrition, Latest News, Research and Developments

by Dan Roberts You’ve heard it before: “Tobacco Smoking Is A Major Cause Of Age Related Macular Degeneration”. According to most research, individuals 65 years of age and over double their risk of developing age-related macular degeneration (AMD) if they smoke. Why? Because tobacco smoking: Reduces levels of plasma antioxidant, a substance in the blood
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March 6, 2016

Experimental Gene Therapies Still Raising Hopes

Posted in: Latest News, Research and Developments

Wills Eye Hospital has announced that it has treated the first RESCUE trial patient in the United States enrolled in an FDA-approved gene therapy vision research study. A product called GS010 (GenSight Biologics), can be injected right into the eye and, in a sense, “re-wire” or lower the patient’s risk for getting the disease. The patient has
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February 27, 2016

Future Sustained Drug Delivery Methods for Choroidal Neovascularization

Posted in: Latest News, Research and Developments

During the American Academy of Ophthalmology’s Retina Subspecialty Day in 2015, Peter K. Kaiser, MD, described six alternative methods being looked at for delivery of anti-VEGF drugs into the retinas of individuals experiencing choroidal neovascularization (CNV). Periodic intraocular injections are currently the only procedure for halting damaging blood vessel growth and leakage. Injections are expensive, time-consuming, and burdensome on the patients, so
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