Research and Developments

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February 15, 2016

New Combination Therapy Treats Retinal Damage in Diabetics

Posted in: Latest News, Research and Developments

Aerpio Therapeutics, Inc. has announced promising results from their “TIME-2” study of  AKB-9778 as a treatment for diabetic retinopathy (DR). AKB-9778 alone and in combination with Lucentis® (ranibizumab) improved underlying retinopathy by 10.0%, and 11.4% compared to 8.8% of patients receiving Lucentis® alone. The clinical findings were presented by Pravin U. Dugel, M.D., at the
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February 10, 2016

AVA-101 May Extend Time Between Wet AMD Treatments

Posted in: Latest News, Research and Developments

In 2014, Avalanche Biotechnologies postulated that a single injection of a new gene therapy treatment could possibly stop blood vessel growth and leakage in the wet form of Age-Related Macular Degeneration (AMD) for several years. A single injection of a drug called AVA-101 (aka sFlt-1) could create a kind of biofactory that continuously secretes a therapeutic protein
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February 5, 2016

High Dose Statins May Be Effective In Treating Dry AMD

Posted in: Latest News, Research and Developments

Researchers at Massachusetts Eye and Ear/Harvard Medical School and the University of Crete have found that high doses of statins (cholesterol-lowering medications) can effectively reduce the number of soft drusen deposits in retinas of people with dry age-related macular degeneration (dAMD). The findings from their phase I/II clinical trial were published in the recent issue of
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February 3, 2016

Accessible Driving Is On The Horizon

Posted in: Latest News, Research and Developments

by Dan Roberts A couple of changes are on the horizon which may allow visually impaired people to regain or maintain the pleasure of piloting their own private vehicles whenever and wherever they choose. The most immediate change could come from relaxation of the minimum visual acuity requirements, made possible in part by the development of bioptic
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January 27, 2016

New Drug Under Study for Dry MD

Posted in: Latest News, Research and Developments

Ophthotech Corporation has announced that the first patient has been dosed in a Phase 2/3 clinical study of Zimura® (avacincaptad pegol sodium) for treatment of advanced dry macular degeneration (MD).  Zimura® is an inhibitor of complement factor C5, a central component of the complement cascade believed to be involved in the development of AMD. The Company has also recently
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January 25, 2016

Let’s Be Clear About Blue Light

Posted in: Latest News, Research and Developments

Editorial by Dan Roberts The media is becoming saturated with warnings about the so-called “blue light hazard”. Let’s pull it back a bit by being more specific about who should be most concerned. In 2006, I published a paper titled Artificial Lighting and the Blue Light Hazard. The purpose of the paper was to warn of
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January 13, 2016

New Study Underway for Treatment of Dry Macular Degeneration

Posted in: Latest News, Research and Developments

Subjects are being sought for trials to test the new Nova Oculus™ device as the only scientifically supported treatment for dry macular degeneration. Presently, no scientifically proven treatment option is available for those with dry macular degeneration (dMD). Ongoing research, however, is showing that a new device using biocurrent technology (very low micro-current electrical stimulation)
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December 11, 2015

Triple Therapy with Zeaxanthin Lessens Burden of Treatment for Wet AMD

Posted in: Health and Nutrition, Latest News, Research and Developments

As far back as 2007, triple therapy for wet (neovascular) age-related macular degeneration (AMD) was shown to be superior to mono therapy (intraocular injection of a single anti-VEGF drug).* And now, a study described in a recent online publication of the peer-reviewed monthly, International Journal of Retina and Vitreous, found that triple therapy supplemented with
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December 10, 2015

Delayed Dark Adaptation Predicts Onset of Dry AMD

Posted in: Latest News, Research and Developments

A recent study* at the University of Alabama has found that measurement of the time it takes older adults’ eyes to adapt to the dark can predict onset of dry age-related macular degeneration (dAMD). Using a computerized dark adaptometer, 325 persons with healthy eyes were each subjected to a flash of light in one eye,
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November 16, 2015

X-82 Oral Medication May Reduce Number of Intravitreal Injections for Wet AMD

Posted in: Latest News, Research and Developments

No cure yet exists for wet AMD, but three FDA-approved therapies are slowing the progress of wet AMD and reducing the amount of vision loss. These treatments are ranibizumab (Lucentis), aflibercept (Eylea), and off-label bevacizumab (Avastin). These medications are highly successful, but they must be injected directly into the eye, and the treatment often needs
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