Therapies, Treatments, and Procedures

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June 29, 2017

Anti-VEGF Treatment Should Not Be Expected to Improve Vision

Posted in: Latest News, Therapies, Treatments, and Procedures

Clearing up a misunderstanding Anti-VEGF drugs for treating wet age-related macular degeneration are highly successful at inhibiting neovascularization, but they are limited to that alone. Clinical trials for Lucentis (ranibizumab) and Eylea (aflibercept) are showing better than 90% success at blocking the growth factors responsible for uncontrolled blood vessel growth into the retina, and off-label
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May 23, 2017

Summary of Research and Developments–2017

Posted in: Daily Living, Latest News, Low Vision Rehabilitation, Research and Developments, Therapies, Treatments, and Procedures

Presentation to the International Low Vision Support Group June 1, 2017 Dan Roberts INTRODUCTION This is my 12th annual summary of leading research and developments occuring during the past 12 months in the fields of blindness and low vision. Sources for further information will appear beneath each topic heading, but for the sake of brevity,
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February 27, 2017

Bright Flash Retinal Photography–a Thing of the Past

Posted in: Latest News, Therapies, Treatments, and Procedures

by Dan Roberts (Macular Degeneration Support) and Liz Trauernicht (Macular Degeneration Foundation) OCT and nonmydriatic technologies are lessening discomfort and risk of eye exams. MD Support and MD Foundation communicate with thousands of patients who undergo periodic eye exams for diagnosis and treatment of macular degeneration, glaucoma, diabetic retinopathy, and other chronic diseases. Many have
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January 6, 2017

Lucentis® Approved for Myopic Macular Degeneration

Posted in: Latest News, Research and Developments, Therapies, Treatments, and Procedures

Genentech has announced FDA approval for Lucentis® as a treatment for patients with choroidal neovascularization (CNV) resulting from myopic macular degeneration (MMD), also known as myopic degeneration. Severe myopia (near-sightedness) can cause uncorrectable central vision impairment, and it may advance to total central vision loss from CNV, which is growth and leakage of blood vessels
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June 9, 2016

For Some, Switching ANTI-VEGF Treatments Midstream Could Be Harmful

Posted in: Latest News, Research and Developments, Therapies, Treatments, and Procedures

Switching from Lucentis to Eylea could result in worsening of the retinal condition of some people with wet (exudative) AMD. Since the advent of anti-VEGF drug treatments for wet AMD, research has verified that blood vessel growth and leakage (neovascularization) usually diminishes in patients who are switched from either Lucentis or Avastin to Eylea. A small
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May 3, 2016

AMD Since Anti-VEGF

Posted in: Latest News, Therapies, Treatments, and Procedures

A National Eye Institute (NEI) study* confirms that anti-VEGF treatments have greatly improved the prognosis for patients with the wet form of age-related macular degeneration (wAMD) during the past decade. In the study of nearly 650 people, half still had vision 20/40 or better, typically good enough to drive or to read standard print, after five years of treatment with
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November 16, 2015

Iluvien Similar to Anti-VEGF Drugs as Treatment for Diabetic Retinopathy

Posted in: Latest News, Research and Developments, Therapies, Treatments, and Procedures

On February 16, Charles C. Wykoff, MD, PhD, announced to the American Academy of Ophthalmology annual meeting that Iluviuan (fluocinolone acetonide) treatment, after 1.3 injections over 3 years in the FAME trials, “significantly reduced progression to prolific diabetic retinopathy from 31% to 17%, a similar reduction as observed with monthly anti-VEGF treatments.” Iluvian (Alimera Sciences)
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November 16, 2015

Lucentis effective for proliferative diabetic retinopathy

Posted in: Latest News, Therapies, Treatments, and Procedures

NIH-funded clinical trial marks first major advance in therapy in 40 years A clinical trial funded by the National Institutes of Health has found that the drug ranibizumab (Lucentis) is highly effective in treating proliferative diabetic retinopathy. The trial, conducted by the Diabetic Retinopathy Clinical Research Network (DRCR.net) compared Lucentis with a type of laser
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April 3, 2015

Phase 2 Stem Cell Trial To Be Initiated

Posted in: Latest News, Therapies, Treatments, and Procedures

Ocata Therapeutics, Inc. (now owned by Acucela) announced on March 31, 2015 that the company has completed dosing of its Phase 1/2 studies for dry age-related macular degeneration (AMD) and Stargardt’s Macular Degeneration (SMD). A total of 38 patients have been safely dosed. The 200,000 cell cohort, the highest level planned, was successfully completed, paving
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February 7, 2015

FDA approves Lucentis to treat diabetic retinopathy in patients with diabetic macular edema

Posted in: Latest News, Therapies, Treatments, and Procedures

The U.S. Food and Drug Administration announced today that they have expanded the approved use for Lucentis 0.3 mg (Genentech) to treat diabetic retinopathy in patients with diabetic macular edema. The FDA previously had approved Lucentis to treat DME and macular edema secondary to retinal vein occlusions, both of which cause fluid to leak into
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