News & Info


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September 29, 2008

POT-4 for Treatment of AMD

Posted in: Research and Developments

by Dan Roberts (Updated September 29, 2008) Potentia Pharmaceuticals, Inc. announced on March 20, 2007 that it was entering the clinical phase of development of POT-4 for treatment of age-related macular degeneration (AMD). According to the researchers, POT-4, a synthetic peptide, shuts down the complement activation system that can lead to local inflammation, tissue damage
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September 22, 2008

Pearls from Recent Studies on Low Vision Rehabilitation and Psychosocial Issues

Posted in: Daily Living, Research and Developments

Research of interest to the AMD Community as presented at Vision 2008, Montreal, Canada Selected and Summarized by Dan Roberts, Director, MD Support These findings are derived by the referenced authors based solely upon the results of their respective studies. In every case, more research is recommended before final conclusions can be drawn. Pearl #1.
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August 28, 2008

New Dry AMD Gene Found

Posted in: Latest News, Research and Developments

by Dan Roberts As reported in the Aug. 28, 2008 online edition of the New England Journal of Medicine, researchers have found a genetic link associated with dry AMD. That’s the good news. The bad news is that siRNA drug therapy may increase the risk for dry AMD in patients who have that genetic variant.
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August 23, 2008

Cone-Rod Dystrophy

Posted in: Eye Conditions

by Dan Roberts (Updated February 21, 2016) Cone-Rod Dystrophy (CRD) is an inherited progressive disease that causes deterioration of the cone and rod photoreceptor cells and often results in blindness. It can be found as an autosomal dominant trait, but it is usually acquired as autosomal recessive. Symptoms of CRD are seen as decreased visual
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July 7, 2008

Lutein And Zeaxanthin May Offer Protection Against MD

Posted in: Health and Nutrition

by Dan Roberts 1995 (Updated July 2008) Progress is being made in the study of both lutein and zeaxanthin as potentially effective nutritional supplements for macular degeneration patients. According to a 1995 study, increasing the consumption of dark green, leafy vegetables appears to offer some protection against macular degeneration. Because nutritional factors may play a
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June 1, 2008

Summary of Research and Developments in Macular Degeneration: 2007-2008

Posted in: Research and Developments

Compiled and edited by Dan Roberts JUNE 2007 Omega-3 Proving to be Beneficial on Several Fronts Recent studies have shown that Omega-3 fatty acids and fish consumption may reduce the risks of age-related macular degeneration (AMD), Alzheimer’s disease, inflammation and depression. The Age-Related Eye Disease Study (AREDS) Research Group showed that dietary total Omega-3 and
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May 15, 2008

The Macular Disease Patient Charter

Posted in: Low Vision Rehabilitation

The Macular Disease Patient Charter, a bill of rights for people with macular disease, was developed and endorsed by AMD Alliance International in May 2008. The charter is a tool designed to outline the rights of people living with macular disease. It encourages them to seek the high quality of care they deserve through a
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May 6, 2008

Sunglasses and Macular Degeneration

Posted in: Daily Living

by Dan Roberts May 2008 Why wear sunglasses? If you have a retinal disease, you are probably photosensitive, where too much direct light is painful for your eyes. You also have retinal cells that can be easily damaged by too much light, and some colors of light (even invisible light) have been shown to be
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April 28, 2008

Gene Therapy Breakthrough

Posted in: Latest News, Research and Developments

by Dan Roberts April 28, 2008 According to two studies published in the New England Journal of Medicine*, doctors have, for the first time, used gene replacement therapy to restore vision in patients with Leber’s congenital amaurosis. Leber’s syndrome is a form of retinitis pigmentosa (RP) that affects children and often leads to blindness by
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March 19, 2008

Müller Cells May Restore Sight

Posted in: Latest News, Research and Developments

by Dan Roberts March 19, 2008 Over the past several years, scientists have been taking an interest in certain cells within the patient’s own eyes as having the potential to transform into stem-like (progenitor) cells. Called Müller glial cells, they would then migrate to damaged areas of the retina and replace dead cells, restoring vision
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March 17, 2008

Robo-4 and Slit2 May Team Up Against Wet AMD

Posted in: Latest News, Research and Developments

by Dan Roberts March 17, 2008 “Robo-4” sounds like a movie by Arnold Schwarzenegger, but in this case, it is a link to another potential treatment for wet AMD. Short for “Roundabout,” Robo-4 is a protein receptor found on the surface of blood vessel cells. When it binds with another protein called Slit2, the combination
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February 28, 2008

CD36 Deficiency May Cause Dry AMD

Posted in: Research and Developments

by Dan Roberts February 2008 CD36 is a protein molecule (called an “integral membrane protein”) permanently attached to the surface of certain human cells. It plays a role in the inflammation process, but researchers have now discovered that a deficiency of the protein may cause the dry form of macular degeneration. Researchers reported that deficiency
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February 28, 2008

AMD Associated With Heart Attack and Stroke

Posted in: Research and Developments

by Dan Roberts Researchers at the University of Sydney have found that people suffering from AMD have twice the risk of dying from heart attack or stroke. 3,654 people aged 49 years old and older, were studied. Five years later, 2,335 people were re-examined, and after 10 years, 1,952 were re-examined. When the study began,
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February 23, 2008

SAILOR Study Results Favorable

Posted in: Latest News, Research and Developments

by Dan Roberts February 23, 2008 The final results from Cohort 1 of the Phase IIIb SAILOR study of Lucentis in patients with wet AMD were presented on February 23, 2008 at the Bascom Palmer Eye Institute’s Angiogenesis meeting by Dr. David Boyer (Retina-Vitreous Associates Medical Group, Los Angeles). The final, one-year data support the
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February 1, 2008

Retina Developed From Human Stem Cells

Posted in: Latest News, Research and Developments

by Dan Roberts (Updated February 1, 2008) Advanced Cell Technology (ACT) in Massachusetts announced on September 23, 2004 that they had engineered human embryonic stem cells which could be used to repair a damaged retina. The research team worked with stem cells taken from human embryos made by another team at Harvard University and coaxed
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