by Dan Roberts Updated March 30, 2015 A means of delivering drugs into the retina on a time release basis is being developed and proven safe and effective. It is achieved by a method called Encapsulated Cell Technology (ECT), being tested by Neurotech SA with support from the National Eye Institute (NEI), Bethesda, Maryland. A [Read More]
Category: Research and Developments
Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration
The CATT Research Group April 2011 In 2005, clinical trials established the efficacy of ranibizumab (Lucentis, Genentech) for the treatment of neovascular age-related macular degeneration (AMD), the leading cause of legal blindness in the United States. While awaiting approval for ranibizumab from the Food and Drug Administration, ophthalmologists began treating neovascular AMD with off-label use [Read More]
A Primer on the Use of Stem Cells in Ophthalmology
Irving J. Arons September 2, 2010 (Version 3, Updated September 14, 2010) I recently came across an interesting news release from International Stem Cell Corporation (ISCO) announcing that it had formed a new business unit, Cytovis, to focus on stem cell programs in ophthalmology, including CytoCor for the cornea and CytoRet for the retina. That [Read More]
Spikes in IOP May Result From Particulate Matter in Avastin
by Dan Roberts In a presentation to Hawaiian Eye 2010, Malik Y. Kahook, MD, said that Avastin (bevacizumab) stored for long periods of time shows evidence of increased large particulate matter. This debris can block the eye’s trabecular network and lead to increased intraocular pressure (IOP) in patients being treated with the drug for wet [Read More]
Genetic testing sheds light on degenerative eye disease
Press Release February 13, 2007 Updated 5/16/2010 ANN ARBOR, Mich. — Genetic testing for eye disease is providing vital information about complex retinal diseases, especially when used to confirm a clinician’s diagnosis. In a newly published review of such tests that were conducted over a five-year period at the University of Michigan Kellogg Eye Center, [Read More]