by Dan Roberts April 20, 2006 Here is a summary of an article that appeared in Science Magazine regarding stem cell transplantation for treatment of retinal degeneration: Stem Cells Promise Cure For Vision Loss Wednesday, April 19, 2006 New Delhi: Dr Rajender Prasad Centre for Opthalmic Sciences at AIIMS has been studying the effect of stem [Read More]
Category: Research and Developments
Gene Therapy Studies Successful in Slowing Neovascularization
by Dan Roberts January 2002 (Updated February 2006) Researchers at Johns Hopkins’ Wilmer Eye Institute have been able to successfully slow blood vessel growth in laboratory mice in two different experiments involving injection of genes, and human trials have begun. In one study (Mori, K., et al., “Inhibition of Choroidal Neovascularization by Intravenous Injection of [Read More]
Drusen Fragments May Lead to Wet AMD
by Dan Roberts February 2006 Dr. Jayakrishna Ambati (University of Kentucky HealthCare physician and Associate Professor and Vice Chair of the Department of Ophthalmology and Visual Sciences), has announced that his lab has identified fragments of two known components of drusen that may be the cause of dry age-related macular degeneration (AMD) progressing to the [Read More]
Gene Therapy Successful in Halting CNV
by Dan Roberts Researchers have been able to halt (at least temporarily) choroidal neovascularization (CNV) with gene replacement therapy. This was done by single injections into the eyeballs of patients during a phase I clinical trial. Here is more detail, as reported on January 17, 2006 by Genetic Engineering News (www.genengnews.com): Clinical Trial on Gene [Read More]
Bacterial Infection Linked to AMD
by Dan Roberts (Updated November 13, 2005) According to a report in the April 2003 issue of the Archives of Ophthalmology (2003;121:478-482.), the bacterium Chlamydia pneumoniae may lead to a higher risk of age-related macular degeneration (AMD). The researchers found that people with AMD tend to carry higher levels of antibodies targeted against C. pneumoniae, [Read More]