A Phase 2 study has found that a new drug could be a safe and effective treatment for improving vision in patients with dry age-related macular degeneration (AMD). On October 13, 2019, David Boyer, MD (Retina-Vitreous Associates Medical Group), presented results from a study of risuteganib intravitreal injection to members of the American Academy of [Read More]
Category: Research and Developments
New treatment approved for wet age-related macular degeneration
Novartis announced on October 8, 2019 that the US Food and Drug Administration (FDA) approved BEOVU® (brolucizumab-dbll) injection for the treatment of wet age-related macular degeneration (wet AMD). This is the fourth anti-VEGF drug treatment to be approved for wet AMD, the others being Lucentis (Genentech), Eylea (Regeneron), and off-label Avastin (Genentech). Similar to its [Read More]
New Sustained Release Drug Enters Trials
Aerie Pharmaceuticals, Inc. (Aerie), has begun patient dosing in their first human clinical trial of a sustained release implant in patients with wet macular degeneration or diabetic macular edema. The polymer implant provides controlled release of AR-13503, an injectable drug that inhibits blood vessel growth in the retina, while potentially reducing the treatment burden associated [Read More]
What Causes Foveal Sparing?
People who have progressed to central vision loss from any one of a number of retinal dystrophies have probably noticed a tiny spot of healthier sight in the very center of the macula (the fovea). Over time, the fovea becomes surrounded by a growing band of blindness, first appearing as individual spots, then coalescing to [Read More]
Stem Cell Treatment for Dry AMD Fast-tracked by FDA
It was reported here in March 2017 that BioTime, Inc. is conducting a Phase I/IIa clinical trial for OpRegen® for treatment of dry AMD. OpRegen is a retinal pigment epithelium (RPE) stem cell transplant therapy currently in development for the treatment of dry age-related macular degeneration (AMD) with geographic atrophy (GA). RPE cells are essential [Read More]