by Dan Roberts (updated April 2009) A new type of anti-VEGF drug called “small interference RNA (siRNA),” is showing promise in its ability to turn off genes that cause wet AMD. A preliminary primate study in early 2004 showed that, at the highest dose used in the study siRNA (formerly called RNAi) “reduced the incidence [Read More]
by Dan Roberts (Updated November 10, 2008) Concentration of two cytokines, interleukin-6 and interleukin-8, have been found in two different studies to be potential biomarkers for incidence of dry AMD. Cytokines are signaling compounds in the cells that are involved in a variety of immunological, inflammatory, and infectious diseases. Janice C. Law, MD, and her [Read More]
by Dan Roberts (Updated November 2015) Overview Myopia is a condition whereby images come into focus in front of the eye, resulting in a blurred image on the retina. The more severe the nearsightedness, the farther the image is from the retina, which results in more blurry vision in the distance. Myopia causes light rays [Read More]
By Linda Kaspari Updated, March 2006 Cigarette smoking reduces levels of plasma antioxidant, a substance in the blood stream, which protects retinal cells. Smoking causes the protective layer between the retina and blood vessels to erode, resulting in poor circulation, irritation and scarring. Smoking is damaging to the blood supply. Smoking exposes the body to [Read More]
by Dan Roberts (Updated November 13, 2005) According to a report in the April 2003 issue of the Archives of Ophthalmology (2003;121:478-482.), the bacterium Chlamydia pneumoniae may lead to a higher risk of age-related macular degeneration (AMD). The researchers found that people with AMD tend to carry higher levels of antibodies targeted against C. pneumoniae, [Read More]