Research and Developments

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October 22, 2004

Human Retinal Stem Cells Discovered

Posted in: Latest News, Research and Developments

by Dan Roberts Research in vision restoration has taken another step forward with the discovery of human retinal stem cells that have the ability to regenerate themselves. The announcement was made in October 2004 to the National Academy of Sciences by Derek Van der Kooy from the Department of Medical Biophysics at the University of
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September 15, 2004

Sight From Fetal Cell Transplantation

Posted in: Latest News, Research and Developments

by Dan Roberts January, 2003 (Updated September, 2004) Scientists are researching a new method of retinal transplantation in the continuing effort to restore sight to the blind. Drs. Robert Aramant and Magdalene Seiler (Doheny Eye Institute, Los Angeles) have had preliminary success transplanting double layers of cells from the retinas of aborted fetuses. The two
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July 22, 2004

Second AMD Gene Discovered

Posted in: Latest News, Research and Developments

A second gene, called fibulin 5, has been shown to be related to age-related macular degeneration (AMD). The discovery was announced in the July 22, 2004 issue of the New England Journal of Medicine by a team from the Research Center for Macular Degeneration and Allied Retinal Diseases at the University of Iowa. Earlier research
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February 11, 2004

C-reactive Protein Levels Connected to Macular Degeneration

Posted in: Research and Developments

by Dan Roberts There has been a good deal of excitement about the possible connection between the level of C-reactive protein (CRP) in the blood and various diseases, including macular degeneration. CRP is responsible for the healing benefit of inflammation that occurs when a part of the body is in trouble. If, however, the level
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October 21, 2003

FFB-Sponsored Study Leads to Discovery of New AMD Gene

Posted in: Latest News, Research and Developments

(Press release from the Foundation Fighting Blindness) October 21, 2003 An exciting gene discovery by an FFB-funded researcher adds to the growing proof that macular degeneration can be hereditary. This is the first gene mutation found that is directly tied to age-related macular degeneration (AMD). The discovery of this gene mutation bolsters hope for a
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September 30, 2003

RDH5 Gene Mutation Can Cause Macular Dystrophy

Posted in: Research and Developments

by Dan Roberts September 2003 Japanese researchers have found that mutations in the RDH5 gene can cause macular dystrophy, fundus albipunctatus, and/or night blindness. Twenty-one patients from nineteen different families with fundus albipunctatus were analyzed. Ten of the patients had macular dystrophy. In eighteen, mutations were found in the RDH5. The patients were tested using
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April 30, 2003

Accutane May Inhibit Progression of Stargardt’s Disease

Posted in: Research and Developments

by Dan Roberts April 2003 Accutane, a prescription drug used to treat acne, has been shown to inhibit the development of lipofuscin deposits in the retinas of rodent models. This is promising news for people with Stargardt’s disease. The author of the study is Dr. Gabriel Travis, professor of ophthalmology and biological chemistry at the
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August 15, 2002

New Retinal Vessels Formed From Stem Cells

Posted in: Latest News, Research and Developments

by Dan Roberts August, 2002 Scientists at The Scripps Research Institute (TSRI) have succeeded in forming new retinal blood vessels in mice with ocular disease. The process uses “pluripotent” adult stem cells, which are derived from bone marrow and injected into the vitreous of the eyeball. When in place, these cells develop into endothelial cells
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August 15, 2002

New MD Gene Discovered

Posted in: Latest News, Research and Developments

by Dan Roberts August, 2002 Researchers at the University of Michigan Kellogg Eye Center have discovered a genetic link to a form of macular degeneration. In an article published in August 2002 in Genome (“X-Linked Recessive Atrophic Macular Degeneration from RPGR Mutation,” pp. 166-171, doi:10.1006/geno.2002.6815, Radha Ayyagari, et al) the gene RPGR (associated until now
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April 21, 2002

Carbon Dioxide May Improve Vision in AMD Patients

Posted in: Research and Developments

by Dan Roberts April 2002 AMD patients are benefitting from a new combination drug therapy being tested at the University of Texas Health Science Center at San Antonio (UTHSC). The therapy involves a combination of medicines which includes carbon dioxide, an element which dilates the blood vessels in the retina for the maintenance of proper
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