Research and Developments

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April 30, 2003

Accutane May Inhibit Progression of Stargardt’s Disease

Posted in: Research and Developments

by Dan Roberts April 2003 Accutane, a prescription drug used to treat acne, has been shown to inhibit the development of lipofuscin deposits in the retinas of rodent models. This is promising news for people with Stargardt’s disease. The author of the study is Dr. Gabriel Travis, professor of ophthalmology and biological chemistry at the
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August 15, 2002

New Retinal Vessels Formed From Stem Cells

Posted in: Latest News, Research and Developments

by Dan Roberts August, 2002 Scientists at The Scripps Research Institute (TSRI) have succeeded in forming new retinal blood vessels in mice with ocular disease. The process uses “pluripotent” adult stem cells, which are derived from bone marrow and injected into the vitreous of the eyeball. When in place, these cells develop into endothelial cells
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August 15, 2002

New MD Gene Discovered

Posted in: Latest News, Research and Developments

by Dan Roberts August, 2002 Researchers at the University of Michigan Kellogg Eye Center have discovered a genetic link to a form of macular degeneration. In an article published in August 2002 in Genome (“X-Linked Recessive Atrophic Macular Degeneration from RPGR Mutation,” pp. 166-171, doi:10.1006/geno.2002.6815, Radha Ayyagari, et al) the gene RPGR (associated until now
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April 21, 2002

Carbon Dioxide May Improve Vision in AMD Patients

Posted in: Research and Developments

by Dan Roberts April 2002 AMD patients are benefitting from a new combination drug therapy being tested at the University of Texas Health Science Center at San Antonio (UTHSC). The therapy involves a combination of medicines which includes carbon dioxide, an element which dilates the blood vessels in the retina for the maintenance of proper
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November 21, 2001

Cells From The Iris May Replace Retinal Photoreceptors

Posted in: Research and Developments

by Dan Roberts November 2001 An online publication of the December 2001 publication of Nature Neuroscience has reported that, with genetic manipulation, cells from the iris may be able to replace photoreceptor cells in the retina. In recent experiments, Dr. Masatoshi Haruta of Kyoto University and colleagues took iris cells from rat eyes, then introduced
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November 15, 2001

U-M Scientist Finds Clues in the Development of Light-Sensitive Eye Cells

Posted in: Latest News, Research and Developments

by Betsy Nisbet November 2001 ANN ARBOR, MI – A paper published electronically by Nature Genetics offers important new insights into the development and differentiation of rod and cone photoreceptors, the light-sensitive cells in the eye’s retina that initiate vision and are essential for clear sight. A team led by Anand Swaroop, Ph.D., professor of
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August 22, 2001

Stem Cell Research: Hope With An Ethical Price Tag

Posted in: Research and Developments

by Dan Roberts August 2001 Background On The Research Stem cells are undeveloped structures which are able develop into any of the nearly 220 cell types that make up the human body, and which can theoretically reproduce themselves infinitely. Recent discovery of adult stem cells, or progenitor cells, in the eyes of adult rodents has
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July 15, 2000

Foundation Researchers Use Gene Therapy to Restore Retinal Function in an Animal Model of Retinal Degeneration

Posted in: Latest News, Research and Developments

by Tom Hoglund July 2000 In the July issue of Nature Genetics, Foundation Fighting Blindness-supported researchers used gene replacement therapy to treat a rodent model of retinal degeneration. This is the first published study to show that gene replacement therapy can restore function to photoreceptor cells. These findings also demonstrate that gene replacement therapy can
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July 15, 2000

Researchers Restore Vision In an Animal Model of Childhood Blindness

Posted in: Latest News, Research and Developments

By Tom Hoglund Information Officer, Foundation Fighting Blindness July 2000 In a ground breaking study published in the July issue of The Proceedings of the National Academy of Sciences, researchers rapidly restored lost vision in a mouse model of Leber congenital amaurosis (LCA) using oral doses of a chemical compound derived from vitamin A. LCA
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July 1, 2000

Artificial Retina Implanted in Humans

Posted in: Latest News, Research and Developments, Therapies, Treatments, and Procedures

by Tom Hoglund Information Officer, Foundation Fighting Blindness For the first time ever, researchers from a company called Optobionics surgically implanted an artificial retina into three patients who are blind from retinitis pigmentosa. These highly-experimental prosthetic devices, made of silicon computer chips, are intended to restore ambulatory vision, thereby giving people the freedom to walk
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