Cognitive Decline Associated With AMD

Investigators have found significant associations between lessened brain functions and age-related macular degeneration (AMD). 5604 people age 40+ who participated in the 2005-2008 National Health and Nutrition Examination Survey have been found to experience increased memory problems and confusion, seemingly as a result of their AMD. The report was published in the December 2019 issue [Read More]

“Bitterness Gene” May Explain Aversion To Vegetables

The first rule of nutrition for maintaining good retina health is, for some people, the most difficult to swallow. Consuming a diet rich in leafy green vegetables for their high antioxidant values is highly recommended by professional nutritionists and eye care specialists, and no one argues about its preventative value. So why is this rule [Read More]

Zimura® for Dry AMD Continues to Show Positive Results in Trials

In January 2017, Ophthotech Corporation (now known as Iveric), announced that the first patient had been dosed in a Phase 2/3 clinical study of Zimura® (avacincaptad pegol sodium) for treatment of advanced dry macular degeneration (aka geographic atrophy). Zimura® inhibits complement factor C5, which is believed to be involved in the development of AMD. On Oct. 28, [Read More]

Positive Results From RGX-314 Gene Therapy

(Updated 9/10/2020) As reported here in 2017, a drug called RGX-314 is being tested as a one-time sub-retinal injection for wet age-related macular degeneration (wAMD). A preliminary study showed that patients with wAMD had long-term vision stabilization and anatomic improvement following a single treatment with the investigational gene therapy. Now, in a subgroup of patients [Read More]