Gene Therapy Breakthrough

by Dan Roberts April 28, 2008 According to two studies published in the New England Journal of Medicine*, doctors have, for the first time, used gene replacement therapy to restore vision in patients with Leber’s congenital amaurosis. Leber’s syndrome is a form of retinitis pigmentosa (RP) that affects children and often leads to blindness by [Read More]

Müller Cells May Restore Sight

by Dan Roberts March 19, 2008 Over the past several years, scientists have been taking an interest in certain cells within the patient’s own eyes as having the potential to transform into stem-like (progenitor) cells. Called Müller glial cells, they would then migrate to damaged areas of the retina and replace dead cells, restoring vision [Read More]

Robo-4 and Slit2 May Team Up Against Wet AMD

by Dan Roberts March 17, 2008 “Robo-4” sounds like a movie by Arnold Schwarzenegger, but in this case, it is a link to another potential treatment for wet AMD. Short for “Roundabout,” Robo-4 is a protein receptor found on the surface of blood vessel cells. When it binds with another protein called Slit2, the combination [Read More]

SAILOR Study Results Favorable

by Dan Roberts February 23, 2008 The final results from Cohort 1 of the Phase IIIb SAILOR study of Lucentis in patients with wet AMD were presented on February 23, 2008 at the Bascom Palmer Eye Institute’s Angiogenesis meeting by Dr. David Boyer (Retina-Vitreous Associates Medical Group, Los Angeles). The final, one-year data support the [Read More]

Retina Developed From Human Stem Cells

by Dan Roberts (Updated February 1, 2008) Advanced Cell Technology (ACT) in Massachusetts announced on September 23, 2004 that they had engineered human embryonic stem cells which could be used to repair a damaged retina. The research team worked with stem cells taken from human embryos made by another team at Harvard University and coaxed [Read More]