(Updated 4/17/16) On June 24, 2014, Ohr Pharmaceutical, Inc. announced positive top-line interim results for its Phase 2 clinical trial of Squalamine eye drops in patients with wet age-related macular degeneration (wet AMD). The data demonstrated a positive benefit in multiple visual function including a gain in visual acuity of +10.4 letters with Squalamine eye [Read More]
Category: Research and Developments
Omega-3 Inhibits Retinal Blood Vessel Growth
Researchers from Massachusetts Eye and Ear/Schepens Eye Research Institute, Harvard Medical School and other institutions have demonstrated for the first time that the omega-3 long-chain polyunsaturated fatty acids (LCPUFAs), DHA and EPA, can inhibit choroidal neovascularization (CNV). Their findings will be published in PNAS Online Early Edition the week of June 16-20, 2014. “These are [Read More]
Stem Cell Trial for Myopic Macular Degeneration
Advanced Cell Technology (ACT) announced in a shareholders’ conference call on June 9, 2014, that it has initiated its myopic macular degeneration (MMD) trial at Jules Stein Eye Institute at UCLA. The open-label study will enroll 12 patients, with cohorts of 3 patients each in an ascending dosage format. As with it’s current trials for [Read More]
Making artificial vision look more natural
Courtesy: National Eye Institute, National Institutes of Health (NEI/NIH) NIH-funded study could help improve retinal prosthetic devices In laboratory tests, researchers have used electrical stimulation of retinal cells to produce the same patterns of activity that occur when the retina sees a moving object. Although more work remains, this is a step toward restoring natural, [Read More]
Experimental Therapies for CSR
by Dan Roberts April 2014 Updated August 18, 2018 Research has shown that corticosteroids produced by the body (endogenous) and administered externally (exogenous) can raise adrenaline levels, which can harm the central retina. Some people have high levels of endogenous steroids that can lead to a condition called central serous retinopathy (CSR), aka central serous [Read More]