Identifying the genetics of retinal degeneration has become especially important with progress of trials in gene therapy. Investigators have identified more than 200 retinal degeneration disease genes, but still haven’t been able to find the cause of disease in up to half of cases. Now Ocular Genomics Institute has announced that Drs. Michael Farkas, Eric [Read More]
Category: Research and Developments
What Should I Ask My Doctor?
by Dan Roberts Updated September 2018 One of the most common problems encountered by people who are first diagnosed with macular degeneration is what to ask the doctor. The news usually takes us by surprise, and we may have never even heard of the disease before. To compound our confusion, many doctors do not have [Read More]
New Anti-PDGF Aptamer Now in Trials
by Dan Roberts February 15, 2008 Ophthotech has begun the first phase of a clinical trial of E10030, an anti-platelet derived growth factor aptamer being developed for treating wet AMD. The trial will evaluate the safety and tolerability of E10030 in combination with an antiangiogenic drug. The hope is that the combination will result in [Read More]
Summary of Research and Developments in Macular Degeneration, 2012-2013
by Dan Roberts June 2013 INTRODUCTION This is a summary of reports about significant research and development in the field of macular degeneration and related diseases presented since June 2012 and May 2013. I will briefly describe the conclusions of 77 studies that have been presented in the areas of therapy, prevention, technology, nutrition and [Read More]
A Guide to Research in Dry AMD
Compiled by Dan Roberts (Updated 8/7/2023) What Is Geographic Atrophy? Geographic atrophy (GA) is a late stage of “dry” age-related macular degeneration (AMD) presenting with gradual deterioration of the photoreceptor and retinal pigment epithelium (RPE) layers of the retina. The main symptom is the absence of vision in one or more areas of the central [Read More]