News

Anti-VEGF Treatment Should Not Be Expected to Improve Vision

Clearing up a misunderstanding Anti-VEGF drugs for treating wet age-related macular degeneration are highly successful at inhibiting neovascularization, but they are limited to that alone. Clinical trials for Lucentis (ranibizumab) and Eylea (aflibercept) are showing better than 90% success at blocking the growth factors responsible for uncontrolled blood vessel growth into the retina, and off-label [Read More]

New One-time Gene Therapy For Wet AMD Could Replace Regular Injections

A new drug called RGX-314 is being developed as a one-time sub-retinal injection for wet AMD. This would be a significant improvement over current anti-VEGF therapies requiring repetitive and frequent intraocular injections. REGENXBIO Inc. has announced that the first human patient has been dosed in a phase I clinical trial of RGX-314. The drug has [Read More]