Researchers at Oxford University have reported successful findings from their Phase 1/2 clinical testing of the CHM gene for treatment of choroideremia. Choroideremia is a rare disease affecting mostly males that leads to blindness. In the multicentre clinical trial, six male patients (aged 35—63 years) all showed improvement after replacement of the malfunctioning gene. The [Read More]
Tag: gene
PEG-POD – New Gene Delivery Tool
by Dan Roberts January 2010 Researchers have developed a new tool for gene therapy that significantly increases gene delivery to cells in the retina compared to other carriers and DNA alone. The study was published in the January 2010 issue of The Journal of Gene Medicine by Tufts University School of Medicine and the Sackler [Read More]
Second AMD Gene Discovered
A second gene, called fibulin 5, has been shown to be related to age-related macular degeneration (AMD). The discovery was announced in the July 22, 2004 issue of the New England Journal of Medicine by a team from the Research Center for Macular Degeneration and Allied Retinal Diseases at the University of Iowa. Earlier research [Read More]