Gene Therapy Successful in Halting CNV

by Dan Roberts Researchers have been able to halt (at least temporarily) choroidal neovascularization (CNV) with gene replacement therapy. This was done by single injections into the eyeballs of patients during a phase I clinical trial. Here is more detail, as reported on January 17, 2006 by Genetic Engineering News (www.genengnews.com): Clinical Trial on Gene [Read More]

Phototrop Improves Vision in ARMD Patients

by Dan Roberts July 13, 2005 Phototrop (a combination of compounds which affect mitochondrial lipid metabolism) is now available in the United States. The compound was reported to yield significant results in a paper published in May 2005. (“Improvement of visual functions and fundus alterations in early age-related macular degeneration treated with a combination of [Read More]

Mouse Model Developed for AMD and Stargardt's Research

by Dan Roberts March 2005 A research team at the University of California, San Diego (UCSD) School of Medicine and the University of Utah have developed a mouse model of Age-Related Macular Degeneration (AMD) and Stargardt’s disease. As reported in the online edition of the Proceedings of the National Academy of Sciences (March 4, 2005), [Read More]

Stem Cells Have Restored Vision

by Dan Roberts November 2004 Scientists from Harvard’s Schepens Eye Research Institute have, for the first time, successfully improved the vision of mice with transplanted stem cells. Neural stem (progenitor) cells were obtained from day-old mice and grafted into the degenerating retinas of mature mice. The transplanted cells were then seen to develop into mature [Read More]